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Primary hypersomnia is defined by excessive daytime sleepiness in the absence of known causes of sleepiness.

An abnormal protein in cerebrospinal fluid appears to cause hypersomnia, a form of excessive daytime sleepiness, and an off-the-shelf drug effectively treated it, researchers said.

Extracted from patients with primary hypersomnia, the elusive substance, which was not fully isolated in the study, enhanced the sensitivity of subtype A gamma-aminobutyric acid (GABA) receptors, reported David Rye, MD, PhD, of Emory University in Atlanta, and colleagues.

Moreover, seven patients ...

Weight loss, particularly abdominal fat loss, improves sleep quality in people who are overweight or obese, new research finds.

Losing weight — through diet alone or diet and exercise combined — might be the ticket to sounder sleep in people who are overweight or obese, researchers from the Johns Hopkins School of Medicine report at the American Heart Association Scientific Sessions in Los Angeles.

A loss of belly fat in particular was associated with better sleep quality in the study’s 77 participants, ...

A gene that regulates sleep and circadian rhythm may also be linked to aging, according to a new study, which may explain the increased risk for diseases that accompany poor sleep habits.

A lack of sleep can contribute to a host of negative health effects, and researchers say they now understand why. Working in mice, researchers found that a gene called SIRT1, which regulates circadian rhythm and sleep, is also linked to aging, according to a study published today in the ...